Brand Name:

Efabiovir®^®

Generic Name:

Efavirenz

Pharmacotherapeutic Group:

Antiviral(systemic)

Therapeutic Indication:

Efabiovir in combination with other antiretroviral agents is indicated for the treatment of HIV-1 infection.

Dosage and Administration:

The recommended dosage of Efabiovir is 600 mg, once daily, in combination with a protease inhibitor and/or nucleoside analogue reverse transcriptase inhibitors (NRTIs).

Side Effects:

COMMON :

• Dermatologic: Pruritus, Rash 
• Endocrine metabolic: Serum triglycerides raised, grades 3 to 4
• Gastrointestinal: Diarrhea, Nausea
• Hepatic: ALT (SGPT) level raised, grades 3 to 4, AST/SGOT level raised, grades 3 to 4, Gamma-glutamyl transferase raised, grades 3 to 4
• Neurologic: Dizziness, Headache, Insomnia
• Psychiatric: Depression, Unable to concentrate
• Other: Fever

SERIOUS :

• Dermatologic: Rash, grade 4
• Psychiatric: At risk for suicide, Depression (Severe), Psychotic disorder, Suicidal thoughts