Anti Viral
Nelfabiovir®
Brand Name:
Nelfabiovir®
Dosage:
250 mg
Generic Name:
Nelfinavir
Pharmacotherapeutic Group:
Antiviral (systemic)
Therapeutic Indication:
Nelfinavir: Nelfabiovir in combination with other antiretroviral agents is indicated for the treatment of HIV infection.
Dosage and Administration:
- Adults: The recommended oral dose is 750mg (three 250mg tablets) 3 times daily in combination with nucleoside analogs.
- Pediatric patients (2 to 13 years of age): 20 – 30 mg/kg/dose, 3 times a day.
Side Effects:
- Body as a Whole: abdominal pain, accidental injury, allergic reaction, asthenia, back pain, fever, headache, malaise, redistribution/accumulation of body fat.
- GI: anorexia, dyspepsia, epigastric pain, gastrointestinal bleeding, hepatitis, mouth ulceration, pancreatitis and vomiting.
- HEM: anemia, leukopenia and thrombocytopenia.
- Metabolic: increases in alkaline phosphate, amylase, creatine phosphokinase, lactic dehydrogenase, SGOT, SGPT and gamma glutamyl transpeptidase; hyperlipemia, hyperuricemia, hyperglycemia, hypoglycemia, bilirubinemia, metabolic acidosis, dehydration and liver function tests abnormal.
- Musculoskeletal: arthralgia, arthritis, cramps, myalgia, myasthenia, myopathy.
- NS: anxiety, depression, dizziness, emotional lability, hyperkinesia, insomnia, migraine, paresthesia, seizures, sleep disorder, somnolence, suicide ideation.
- RESP: dyspnea, pharyngitis, rhinitis, and sinusitis.
- Skin/Appendages: dermatitis, folliculitis, fungal dermatitis, maculopapular rash, pruritus, sweating, and urticaria.
- Special Senses: acute iritis and eye disorder.
- Urogenital System: kidney calculus, sexual dysfunction and urine abnormality.
