Anti Viral

Ledibiox®

Brand Name:

Ledibiox®

Dosage:

90/400

Generic Name:

Ledipasvir / Sofosbuvir

Pharmacotherapeutic Group:

Anti Viral

Therapeutic Indication:

Ledibiox is indicated for the treatment of chronic hepatitis C (CHC) genotype 1 infection in adults.

Dosage and Administration:

The recommended dose for Ledibiox is one tablet (90 mg of ledipasvir and 400 mg of sofosbuvir) taken orally once daily with or without food.

 A dose recommendation cannot be made for patients with severe renal impairment or end stage renal disease.

Side Effects:

The most common adverse reactions with Ledipasvir/Sofosbuvir are fatigue and headache (≥10%). Nausea, diarrhea and insomnia are observed in ≥5% of patients receiving Ledipasvir/Sofosbuvir treatment. Elevations in bilirubin, lipase and creatine kinase have been reported in less than 3%.

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