CNS

Biomigril®

Brand Name:

Biomigril®

Dosage:

5 mg & 10 mg

Generic Name:

Rizatriptan

Pharmacotherapeutic Group:

Antimigraine Agent

Therapeutic Indication:

Rizatriptan: Biomigril is indicated for the acute treatment of migraine attacks with or without aura in adults.

Dosage and Administration:

Migraine: Oral: 5-10 mg, repeat after 2 hours if significant relief is not attained; maximum: 30 mg in a 24-hour period (use 5 mg dose in patients receiving propranolol with a maximum of 15 mg in 24 hours).

Side Effects:

  • Cardiovascular: Systolic/diastolic blood pressure increases (5-10 mm Hg), chest pain (5%), palpitation
  • Central nervous system: Dizziness, drowsiness, fatigue (13% to 30%, dose related)
  • Dermatologic: Skin flushing
  • Endocrine & metabolic: Mild increase in growth hormone, hot flashes
  • Gastrointestinal: Abdominal pain, dry mouth (<5%), nausea
  • Respiratory: Dyspnea

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