Zyprobiox®
Brand Name:
Zyprobiox®
Dosage:
2.5 mg & 5 mg & 10 mg & 15 mg
Generic Name:
Olanzapine
Pharmacotherapeutic Group:
Antipsychotic
Therapeutic Indication:
Olanzapine: Treatment of schizophrenia;
Short-term treatment of acute manic episodes with bipolar I disorder.
Dosage and Administration:
Schizophrenia:
ADULTS: PO Start with 5 to 10 mg/day and adjust dosage at 5 mg increments in intervals of greater than 1 wk (safety of doses at least 20 mg/day have not been evaluated).Biopolar Mania:
ADULTS: PO Start with 10 to 15 mg/day and adjust at 5 mg increments in intervals greater than 24 hr (safety of doses more than 20 mg/day have not been evaluated).
Side Effects:
- CV: Hypotension; tachycardia.
- CNS: Somnolence; agitation; insomnia; nervousness; hostility; akathisia; amnesia; impairment of articulation;
- uphoria; stuttering; tardive dyskinesia; anxiety; twitching.
- DERM: Rash.
- EENT: Amblyopia; blepharitis; corneal lesion.
- GI: Constipation; dry mouth; salivation; nausea; vomiting; increased appetite.
- GU: Premenstrual syndrome; hematuria; metrorrhagia; urinary incontinence.
- HEP: Increased LFTs.
- METABOLIC: Weight gain; peripheral edema; lower extremity edema.
- RESP: Rhinitis; cough; pharyngitis; dyspnea.
- OTHER: Headache; flu-like syndrome; fever; dizziness; joint and muscle aches.