Brand Name:

Biopentine ^®

Dosage:

100 mg & 300 mg & 400 mg

Generic Name:

Gabapentin

Pharmacotherapeutic Group:

Anticonvulsant

Therapeutic Indication:

Gabapentin: Adjunctive therapy in treatment of partial seizures with or without secondary generalization in patients above 12 yr with epilepsy. Adjunctive therapy for partial seizures in children 3 to 12 yr. management of postherpetic neuralgia in adults.

Dosage and Administration:

Epilepsy

• ADULTS AND CHILDREN ABOVE 12 YR: PO 900 to 1800 mg/day in divided doses tid. Initial dose: 300 mg on day 1 and titrate upward rapidly.
• CHILDREN 3 TO 12 YR: PO Initiate therapy at 10 to 15 mg/kg/day in divided doses (ie, 3 times/day) and titrate dose upward over a period of about 3 days to the effective dose.
• CHILDREN AT LEAST 5 YR: PO The effective dose is 25 to 35 mg/kg/day in divided doses.
• CHILDREN 3 TO 4 YR: PO The effective dose is 40 mg/kg/day in divided doses.

Postherpetic Neuralgia

ADULTS: PO Start with a single 300 mg dose on day 1, 600 mg on day 2 (divided twice daily), and 900 mg on day 3 (divided 3 times daily). Subsequently, titrate the dose upward as needed for pain relief to a daily dose of 1800 mg (divided 3 times daily).